Het-PDB Navi2 (PDB: 1SYL)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name	Link
DUT	Deoxyuridine-5'-triphosphate	PoSSuM
MG	Magnesium ion	PoSSuM
TRS	2-amino-2-hydroxymethyl-propane-1,3-diol	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 1SYL

Code :

1SYL PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Crystal structure of inactive mutant dUTPase complexed with substrate dUTP

Release Data :

2004-09-07

Compound :

mol_id	molecule	chains	synonym
1	Deoxyuridine 5'-triphosphate nucleotidohydrolase	A	dUTPase, dUTP pyrophosphatase
	ec: 3.6.1.23 mutation: D90N

Source :

mol_id	organism_scientific	expression_system
1	Escherichia coli (taxid:562)	Escherichia coli BL21(DE3) (taxid:469008)
	gene: DUT expression_system_strain: BL21(DE3) expression_system_vector_type: PLASMID expression_system_plasmid: PET22B

Authors :

Barabas, O., Kovari, J., Pongracz, V., Wilmanns, M., Vertessy, B.G.

Keywords :

enzyme-ligand complex, jelly roll, HYDROLASE

Exp. method :

X-RAY DIFFRACTION ( 1.95 Å )

Citation :

Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase

Barabas, O.,Pongracz, V.,Kovari, J. et al.
(2004) J.Biol.Chem. 279 : 42907 - 42915

Atomic resolution structure of Escherichia coli dUTpase determined ab initio

Gonzalez, A.,Larsson, G.,Persson, R. et al.
(2001) Acta Crystallogr.,Sect.D 57 : 767 - 774

Chain :

UniProt :

P06968 (DUT_ECOLI)

PDB ID: 1SYL