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Ligands
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SO4 Sulfate ion
Non-standard Residues
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CAF S-dimethylarsinoyl-cysteine
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Code : 1SNG   PDBj   RCSB PDB   PDBe
Header : HYDROLASE INHIBITOR
Title : Structure of a Thermophilic Serpin in the Native State
Release Data : 2004-12-14
Compound :
mol_id molecule chains
1 COG4826: Serine protease inhibitor A
Source :
mol_id organism_scientific expression_system
1 Thermobifida fusca  (taxid:2021) Escherichia coli  (taxid:562)
expression_system_strain: SG13009(pREP4)
expression_system_vector_type: plasmid
expression_system_plasmid: pQE30
Authors : Fulton, K.F., Buckle, A.M., Cabrita, L.D., Irving, J.A., Butcher, R.E., Smith, I., Reeve, S., Lesk, A.M., Bottomley, S.P., Rossjohn, J., Whisstock, J.C.
Keywords : Serine Protease Inhibitor (Serpin), Native State., HYDROLASE INHIBITOR
Exp. method : X-RAY DIFFRACTION ( 1.76 Å )
Citation :

The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition.

Fulton, K.F.,Buckle, A.M.,Cabrita, L.D.  et al.
(2005)  J.Biol.Chem.  280 : 8435 - 8442

PubMed: 15590653
DOI: 10.1074/jbc.M410206200