Brand  (β version)

PDB ID: 1S9Q

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Ligands
Code Name Style Show Link
OHT 4-hydroxytamoxifen PoSSuM
CHD Cholic acid PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1S9Q   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION
Title : crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with 4-hydroxytamoxifen
Release Data : 2004-06-08
Compound :
mol_id molecule chains synonym
1 Estrogen-related receptor gamma A,B Estrogen receptor related protein 3, ERR gamma-2
Source :
mol_id organism_scientific organism_common expression_system
1 Mus musculus  (taxid:10090) House mouse Escherichia coli BL21(DE3)  (taxid:469008)
gene: ESRRG, NR3B3, ERRG2, ERR3, KIAA0832
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET-15b
Authors : Greschik, H., Flaig, R., Renaud, J.P., Moras, D.
Keywords : ligand-binding domain, antagonist complex, TRANSCRIPTION
Exp. method : X-RAY DIFFRACTION ( 2.20 Å )
Citation :

Structural Basis for the Deactivation of the Estrogen-related Receptor {gamma} by Diethylstilbestrol or 4-Hydroxytamoxifen and Determinants of Selectivity.

Greschik, H.,Flaig, R.,Renaud, J.P.  et al.
(2004)  J.Biol.Chem.  279 : 33639 - 33646

PubMed: 15161930
DOI: 10.1074/jbc.M402195200

Reaction

Chain : A, B
UniProt : P62509 (ERR3_MOUSE)
Reaction : -