Brand  (β version)

PDB ID: 1S5H

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Ligands
Code Name Style Show Link
DGA Diacyl glycerol PoSSuM
F09 Nonan-1-ol PoSSuM
K Potassium ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1S5H   PDBj   RCSB PDB   PDBe
Header : MEMBRANE PROTEIN
Title : Potassium Channel Kcsa-Fab Complex T75C mutant in K+
Release Data : 2004-05-18
Compound :
mol_id molecule chains
1 ANTIBODY FAB FRAGMENT LIGHT CHAIN A
mol_id molecule chains
2 ANTIBODY FAB FRAGMENT HEAVY CHAIN B
mol_id molecule chains
3 Voltage-gated potassium channel C
mutation: P2A, T75C
Source :
mol_id organism_scientific organism_common
1 Mus musculus  (taxid:10090) House mouse
mol_id organism_scientific organism_common
2 Mus musculus  (taxid:10090) House mouse
mol_id organism_scientific organism_common expression_system
3 Streptomyces coelicolor, Streptomyces lividans  (taxid:1902,1916) , Escherichia coli  (taxid:562)
strain: ,
gene: KCSA, SKC1, SCO7660, SC10F4.33
expression_system_strain: XL1 blue
expression_system_vector_type: plasmid
expression_system_plasmid: PQE60
Authors : Mackinnon, R., Zhou, M.
Keywords : K+ CHANNEL, PROTEIN-ANTIBODY FAB COMPLEX, selectivity filter, ion occupancy, MEMBRANE PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.20 Å )
Citation :

A mutant KcsA K(+) channel with altered conduction properties and selectivity filter ion distribution.

Zhou, M.,MacKinnon, R.
(2004)  J.Mol.Biol.  338 : 839 - 846

PubMed: 15099749
DOI: 10.1016/j.jmb.2004.03.020

Reaction

Chain : C
UniProt : Q54397 (multiple entry names are found)
Reaction : -