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Ligands
Code Name Style Show Link
CA Calcium ion
DCP 2'-deoxycytidine-5'-triphosphate
Non-standard Residues
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Glycosylation
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Modification
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Code : 1S10   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE/DNA
Title : Snapshots of replication through an abasic lesion: structural basis for base substitution and frameshift
Release Data : 2004-03-30
Compound :
mol_id molecule chains
1 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*A)-3' B
mol_id molecule chains
2 5'-D(*TP*CP*AP*GP*TP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3' C
mol_id molecule chains synonym
3 DNA polymerase IV A Pol IV
ec: 2.7.7.7
Source :
mol_id organism_scientific
1
synthetic: yes
mol_id organism_scientific
2
synthetic: yes
mol_id organism_scientific expression_system
3 Sulfolobus solfataricus  (taxid:273057) Escherichia coli  (taxid:562)
strain: P2
gene: dpo4
expression_system_vector_type: plasmid
expression_system_plasmid: pET22b
Authors : Ling, H., Boudsocq, F., Woodgate, R., Yang, W.
Keywords : abaic lesion, LESION BYPASS, POLYMERASE, TRANSFERASE-DNA COMPLEX
Exp. method : X-RAY DIFFRACTION ( 2.1 Å )
Citation :

Snapshots of Replication through an Abasic Lesion; Structural Basis for Base Substitutions and Frameshifts.

Ling, H.,Boudsocq, F.,Woodgate, R.  et al.
(2004)  Mol.Cell  13 : 751 - 762

PubMed: 15023344
DOI: 10.1016/S1097-2765(04)00101-7

Chain : A
UniProt : Q97W02 (DPO4_SACS2)
Reaction: EC: Evidence:
Physiological Direction:
a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1) 2.7.7.7 -
-