Brand  (β version)

PDB ID: 1R89

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Ligands
Code Name Style Show Link
CL Chloride ion PoSSuM
CTP Cytidine-5'-triphosphate PoSSuM
MG Magnesium ion PoSSuM
MN Manganese (II) ion PoSSuM
NA Sodium ion PoSSuM
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Structure summary

Code : 1R89   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide Complexes
Release Data : 2003-12-16
Compound :
mol_id molecule chains synonym
1 tRNA nucleotidyltransferase A tRNA adenylyltransferase, tRNA CCA-pyrophosphorylase, CCA-adding enzyme
ec: 2.7.7.25
Source :
mol_id organism_scientific expression_system
1 Archaeoglobus fulgidus  (taxid:2234) Escherichia coli  (taxid:562)
gene: CCA, AF2156
Authors : Xiong, Y., Li, F., Wang, J., Weiner, A.M., Steitz, T.A.
Keywords : CCA Adding Enzyme, Incoming nucleotide, nucleotidyltransferase superfamily, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.80 Å )
Citation :

Crystal structures of an archaeal class I CCA-adding enzyme and its nucleotide complexes

Xiong, Y.,Li, F.,Wang, J.  et al.
(2003)  Mol.Cell  12 : 1165 - 1172

PubMed: 14636575
DOI: 10.1016/S1097-2765(03)00440-4

Reaction

Chain : A
UniProt : O28126 (CCA_ARCFU)
Reaction: EC: Evidence:
Physiological Direction:
a tRNA precursor + ATP + 2 CTP = a tRNA with a 3' CCA end + 3 diphosphate 2.7.7.72 PubMed:14592988, PubMed:25640237
left-to-right
a tRNA with a 3' CCA end + ATP + 2 CTP = a tRNA with a 3' CCACCA end + 3 diphosphate - PubMed:25640237
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