Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
CCI Calicheamicin gamma-1-oligosaccharide
NBU N-butane
Code : 1QMS
Header : DNA
Title : Head-to-Tail Dimer of Calicheamicin gamma-1-I Oligosaccharide Bound to DNA Duplex, NMR, 9 Structures
Release Data : 1999-10-12
Compound :
mol_id molecule chains
1 DNA (5'-D(*GP*CP*AP*CP*CP*TP*TP*CP*CP*TP*GP*C)-3') A
mol_id molecule chains
2 DNA (5'-D(*GP*CP*AP*GP*GP*AP*AP*GP*GP*TP*GP*C)-3') B
other_details: COMPLEXED WITH CALICHEAMICIN HEAD-TO-TAIL DIMER
Source :
mol_id organism_scientific
1 Synthetic construct  (taxid:32630)
synthetic: yes
mol_id organism_scientific
2 Synthetic construct  (taxid:32630)
synthetic: yes
Authors : Bifulco, G., Galeone, A., Nicolaou, K.C., Chazin, W.J., Gomez-Paloma, L.
Keywords : DEOXYRIBONUCLEIC ACID/CALICHEAMICIN, CALICHEAMICIN, HEAD-TO-TAIL DIMER, DNA, MINOR GROOVE BINDING, ANTITUMOR AGENT, LIGAND-DNA COMPLEX, DEOXYRIBONUCLEIC ACID
Exp. method : SOLUTION NMR
Citation :

Solution Structure of the Complex between the Head-to-Tail Dimer of Calicheamicin Gamma-1-I Oligosaccharide and a DNA Duplex Containing D(ACCT) and D(TCCT) High-Affinity Binding Sites

Bifulco, G.,Galeone, A.,Nicolaou, K.C.  et al.
(1998)  J.Am.Chem.Soc.  120 : 7183 - 7191

DOI: 10.1021/ja973910y