Brand  (β version)

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interaction residue:

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Ligands
Code Name Link
SM Samarium (III) ion
Code : 1QAT
Header : HYDROLASE
Title : 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA COMPLEX WITH SAMARIUM (III) CHLORIDE
Release Data : 1997-02-12
Compound :
mol_id molecule chains synonym
1 PHOSPHOLIPASE C DELTA-1 A,B PLC-DELTA-1
ec: 3.1.4.11
other_details: PHOSHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C DELTA-1
Source :
mol_id organism_scientific organism_common expression_system
1 Rattus norvegicus  (taxid:10116) Norway rat Escherichia coli  (taxid:562)
organ: SEED
expression_system_plasmid: PET
Authors : Grobler, J.A., Hurley, J.H.
Keywords : HYDROLASE, LIPID DEGRADATION, TRANSDUCER, CALCIUM-BINDING
Exp. method : X-RAY DIFFRACTION ( 3.0 Å )
Citation :

C2 domain conformational changes in phospholipase C-delta 1.

Grobler, J.A.,Essen, L.O.,Williams, R.L.  et al.
(1996)  Nat.Struct.Biol.  3 : 788 - 795

PubMed: 8784353
DOI: 10.1038/nsb0996-788

Crystal Structure of a Mammalian Phosphoinositide-Specific Phospholipase C Delta

Essen, L.O.,Perisic, O.,Cheung, R.  et al.
(1996)  Nature  380 : 595

Expression, Characterization, and Crystallization of the Catalytic Core of Rat Phosphatidylinositide-Specific Phospholipase C Delta 1

Grobler, J.A.,Hurley, J.H.
(1996)  Protein Sci.  5 : 680

Chain : A, B
UniProt : P10688 (PLCD1_RAT)
Reaction : 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.