Het-PDB Navi2 (PDB: 1Q91)

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Ligands
Code	Name	Link
DPB	(S)-1-[2'-deoxy-3',5'-O-(1-phosphono)benzylidene-B-D-threo-pentofuranosyl]thymine	PoSSuM
MG	Magnesium ion	PoSSuM
PO4	Phosphate ion	PoSSuM

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Download interaction data: 1Q91

Code :

1Q91 PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Crystal structure of human mitochondrial deoxyribonucleotidase in complex with the inhibitor DPB-T

Release Data :

2004-04-20

Compound :

mol_id	molecule	chains	synonym
1	5(3)-deoxyribonucleotidase	A	deoxyribonucleotidase
	ec: 3.1.3.5

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)

Authors :

Rinaldo-Matthis, A., Rampazzo, C., Balzarini, J., Reichard, P., Bianchi, V., Nordlund, P.

Keywords :

alpha-beta-Rossman fold, hydrolase

Exp. method :

X-RAY DIFFRACTION ( 1.60 Å )

Citation :

Crystal structures of the mitochondrial deoxyribonucleotidase in complex with two specific inhibitors

Rinaldo-Matthis, A.,Rampazzo, C.,Balzarini, J. et al.
(2004) Mol.Pharmacol. 65 : 860 - 867

Chain :

UniProt :

Q9NPB1 (NT5M_HUMAN)

Cofactor:	Evidence:	Note:
Reaction :	-
Mg(2+)	-	-

PDB ID: 1Q91