Brand  (β version)

PDB ID: 1Q1Q

Hetero Atom Contents

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
A3P Adenosine-3'-5'-diphosphate PoSSuM
NA Sodium ion PoSSuM
NHE 2-[N-cyclohexylamino]ethane sulfonic acid PoSSuM

Structure summary

Code : 1Q1Q
Header : TRANSFERASE
Title : Crystal structure of human pregnenolone sulfotransferase (SULT2B1a) in the presence of PAP
Release Data : 2003-11-11
Compound :
mol_id molecule chains synonym
1 sulfotransferase family, cytosolic, 2B, member 1 isoform a A SULT2B1a
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: SULT2B1
expression_system_strain: BL21(DE3)RIL
expression_system_vector_type: PLASMID
expression_system_plasmid: PGEX-6P-3
Authors : Lee, K.A., Fuda, H., Lee, Y.C., Negishi, M., Strott, C.A., Pedersen, L.C.
Keywords : sulfotransferase, pregnenolone, SULT2B1, PAP, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.91 Å )
Citation :

Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical SULT2A1 and the SULT2BG1 isoforms.

Lee, K.A.,Fuda, H.,Lee, Y.C.  et al.
(2003)  J.Biol.Chem.  278 : 44593 - 44599

PubMed: 12923182
DOI: 10.1074/jbc.M308312200

Reaction

Chain : A
UniProt : O00204 (ST2B1_HUMAN)
Reaction : 3'-phosphoadenylyl sulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate.