Het-PDB Navi2 (PDB: 1PX5)

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Ligands
Code	Name		Style	Show	Link
SO4	Sulfate ion				PoSSuM

Non-standard Residues
Code	Name	Show
YCM	S-(2-amino-2-oxoethyl)-L-cysteine

Glycosylation
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Download interaction data: 1PX5

Code :

1PX5 PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase

Release Data :

2003-11-25

Compound :

mol_id	molecule	chains	synonym
1	2'-5'-oligoadenylate synthetase 1	A,B	(2-5')oligo(A)synthetase 1, 2-5A synthetase 1, p42 OAS
	ec: 2.7.7.-

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Sus scrofa (taxid:9823)	Pig	Escherichia coli BL21(DE3) (taxid:469008)
	gene: OAS1 expression_system_strain: BL21DE3 expression_system_vector_type: Plasmid expression_system_plasmid: pET15b

Authors :

Hartmann, R., Justesen, J., Sarkar, S.N., Sen, G.C., Yee, V.C.

Keywords :

5-stranded antiparalel beta sheet, four helix bundle, TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 1.74 Å )

Citation :

Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase

Hartmann, R.,Justesen, J.,Sarkar, S.N. et al.
(2003) Mol.Cell 12 : 1173 - 1185

Chain :

A, B

UniProt :

Q29599 (OAS1_PIG)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
3 ATP = 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')- adenosine + 2 diphosphate	2.7.7.84	PubMed:14636576
	-	PubMed:14636576

PDB ID: 1PX5