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Ligands
Code Name Style Show Link
SPM Spermine
Non-standard Residues
Code Name Show
2MU 2',5-dimethyluridine-5'-monophosphate
FA2 5-(6-amino-9h-purin-9-yl)-4-hydroxytetrahydrofuran-3-yl dihydrogen phosphate
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 1PWF   PDBj   RCSB PDB   PDBe
Header : DNA
Title : One Sugar Pucker Fits All: Pairing Versatility Despite Conformational Uniformity in TNA
Release Data : 2004-07-13
Compound :
mol_id molecule chains
1 5'-D(*GP*CP*GP*TP*AP*(2MU)P*(FA2)P*CP*GP*C)-3' A,B
other_details: A-DNA decamer duplex with TNA-adenine and 2'-methoxy-thymine modifications
Source :
mol_id organism_scientific
1
synthetic: yes
other_details: chemically synthesized oligonucleotide
Authors : Pallan, P.S., Wilds, C.J., Wawrzak, Z., Krishnamurthy, R., Eschenmoser, A., Egli, M.
Keywords : A-DNA, Hydrogen Bonding, Nucleic Acid Etiology, Tetrose, Four Carbon Sugar, Nucleic Acid Analogue, DNA
Exp. method : X-RAY DIFFRACTION ( 1.16 Å )
Citation :

Why does TNA cross-pair more strongly with RNA than with DNA? an answer from X-ray analysis.

Pallan, P.S.,Wilds, C.J.,Wawrzak, Z.  et al.
(2003)  ANGEW.CHEM.INT.ED.ENGL.  42 : 5893 - 5895

PubMed: 14673929
DOI: 10.1002/anie.200352553