PDB ID: 1PWD
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0MU | (2r)-5-(acetyloxymethyl)-2-[(1r)-1-[[(5r)-5-azanyl-6-oxidanyl-6-oxidanylidene-hexanoyl]amino]-2-oxidanylidene-ethyl]-5,6-dihydro-2h-1,3-thiazine-4-carboxylic acid | PoSSuM |
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Download interaction data: 1PWD
Structure summary
Code : | 1PWD PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE/Antibiotic | ||||||||||||
Title : | Covalent acyl enzyme complex of the Streptomyces R61 DD-peptidase with cephalosporin C | ||||||||||||
Release Data : | 2004-07-13 | ||||||||||||
Compound : |
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Authors : | Silvaggi, N.R., Josephine, H.R., Pratt, R.F., Kelly, J.A. | ||||||||||||
Keywords : | BETA-LACTAM, ANTIBIOTICS, PENICILLIN BINDING PROTEIN, ENZYME, PEPTIDOGLYCAN, HYDROLASE, HYDROLASE-Antibiotic complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.20 Å ) | ||||||||||||
Citation : |
Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
Silvaggi, N.R.,Josephine, H.R.,Kuzin, A.P.
et al.
PubMed: 15581896 Structures of Two Kinetic Intermediates Reveal Species Specificity of Penicillin-Binding Proteins
Mcdonough, M.A.,Anderson, J.W.,Silvaggi, N.R.
et al.
A 1.2-A Snapshot of the Final Step of Bacterial Cell Wall Biosynthesis
Lee, W.,Mcdonough, M.A.,Kotra, L.
et al.
The Refined Crystallographic Structure of a Dd-Peptidase Penicillin-Target Enzyme at 1.6 A Resolution
Kelly, J.A.,Kuzin, A.P.
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Reaction
Chain : | A | ||||||||
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UniProt : | P15555 (DAC_STRSR) | ||||||||
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