PDB ID: 1PVP
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Download interaction data: 1PVP
Structure summary
Code : | 1PVP PDBj RCSB PDB PDBe | ||||||||||||||||||||||||||||||||||||
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Header : | RECOMBINATION/DNA | ||||||||||||||||||||||||||||||||||||
Title : | BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, ALSHG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7 | ||||||||||||||||||||||||||||||||||||
Release Data : | 2004-02-17 | ||||||||||||||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Baldwin, E.P., Martin, S.S., Abel, J., Gelato, K.A., Kim, H., Schultz, P.G., Santoro, S.W. | ||||||||||||||||||||||||||||||||||||
Keywords : | Cre, recombinase, DNA, CRE-LOXP RECOMBINATION, RECOMBINATION-DNA COMPLEX | ||||||||||||||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.35 Å ) | ||||||||||||||||||||||||||||||||||||
Citation : |
A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Baldwin, E.P.,Martin, S.S.,Abel, J.
et al.
PubMed: 14652076 Directed evolution of the site specificity of Cre recombinase.
Santoro, S.W.,Schultz, P.G.
Modulation of the active complex assembly and turnover rate by protein-DNA interactions in Cre-LoxP recombination.
Martin, S.S.,Chu, V.C.,Baldwin, E.
DOI: 10.1021/bi0272306 The order of strand exchanges in Cre-LoxP recombination and its basis suggested by the crystal structure of a Cre-LoxP Holliday junction complex.
Martin, S.S.,Pulido, E.,Chu, V.C.
et al.
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Reaction
Chain : | A, B |
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UniProt : | P06956 (RECR_BPP1) |
Reaction : | - |