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Ligands
Code Name Style Show Link
DCP 2'-deoxycytidine-5'-triphosphate
EDO 1,2-ethanediol
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Glycosylation
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Code : 1PKK   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii
Release Data : 2003-09-23
Compound :
mol_id molecule chains synonym
1 Bifunctional deaminase/diphosphatase A,B MjDCD-DUT, DCD/DUT
ec: 3.5.4.13, 3.6.1.23
Source :
mol_id organism_scientific expression_system
1 Methanocaldococcus jannaschii  (taxid:2190) Escherichia coli  (taxid:562)
gene: MJ0430
expression_system_strain: BL21 (DE3) RIL
expression_system_vector_type: plasmid
expression_system_plasmid: pET17b
Authors : Huffman, J.L., Li, H., White, R.H., Tainer, J.A.
Keywords : DCTP DEAMINASE, DUTPASE, DCD-DUT, MJ0430, DCTP, DUTP, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 1.77 Å )
Citation :

Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii

Huffman, J.L.,Li, H.,White, R.H.  et al.
(2003)  J.Mol.Biol.  331 : 885 - 896

PubMed: 12909016
DOI: 10.1016/S0022-2836(03)00789-7

Chain : A, B
UniProt : Q57872 (DCDB_METJA)
Reaction: EC: Evidence:
Physiological Direction:
dCTP + 2 H2O = diphosphate + dUMP + NH4(+) 3.5.4.30 HAMAP-Rule:MF_00146, PubMed:12538648, PubMed:12670946
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