Brand  (β version)

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information
centroid:
interaction residue:

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Ligands
Code Name Link
LU Lutetium (III) ion
NAD Nicotinamide-adenine-dinucleotide
Modified Residues
Code Name Link
MSE Selenomethionine
Code : 1PJL
Header : OXIDOREDUCTASE
Title : Crystal structure of human M-NAD-ME in ternary complex with NAD and Lu3+
Release Data : 2003-06-17
Compound :
mol_id molecule chains synonym
1 NAD-dependent malic enzyme, mitochondrial A,B,C,D,E,F,G,H NAD-ME, Malic enzyme 2
ec: 1.1.1.38
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: ME2
Authors : Yang, Z., Batra, R., Floyd, D.L., Hung, H.-C., Chang, G.-G., Tong, L.
Keywords : OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.9 Å )
Citation :

Potent and competitive inhibition of malic enzymes by lanthanide ions

Yang, Z.,Batra, R.,Floyd, D.L.  et al.
(2000)  Biochem.Biophys.Res.Commun.  274 : 440 - 444

PubMed: 10913357
DOI: 10.1006/bbrc.2000.3163

Chain : A, B, C, D, E, F, G, H
UniProt : P23368 (MAOM_HUMAN)
Reaction : (S)-malate + NAD(+) = pyruvate + CO(2) + NADH.
Oxaloacetate = pyruvate + CO(2).