Brand  (β version)

PDB ID: 1PJ6

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Ligands
Code Name Style Show Link
NA Sodium ion PoSSuM
FOL Folic acid PoSSuM
FAD Flavin-adenine dinucleotide PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1PJ6   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with folic acid
Release Data : 2003-10-07
Compound :
mol_id molecule chains
1 N,N-dimethylglycine oxidase A
ec: 1.5.3.10
Source :
mol_id organism_scientific expression_system
1 Arthrobacter globiformis  (taxid:1665) Escherichia coli  (taxid:562)
expression_system_vector_type: plasmid
expression_system_plasmid: puc19
Authors : Leys, D., Basran, J., Scrutton, N.S.
Keywords : channelling, folate binding, FAD binding, amine oxidation, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 1.65 Å )
Citation :

Channelling and formation of 'active' formaldehyde in dimethylglycine oxidase.

Leys, D.,Basran, J.,Scrutton, N.S.
(2003)  Embo J.  22 : 4038 - 4048

PubMed: 12912903
DOI: 10.1093/emboj/cdg395

Reaction

Chain : A
UniProt : Q9AGP8 (DMGO_ARTGO)
Reaction: EC: Evidence:
Physiological Direction:
H2O + N,N-dimethylglycine + O2 = formaldehyde + H2O2 + sarcosine 1.5.3.10 PubMed:11422368
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(6S)-5,6,7,8-tetrahydrofolate + N,N-dimethylglycine + O2 = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O2 + sarcosine - PubMed:11422368
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