Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
N Any 5'-monophosphate nucleotide
Code : 1PHW
Header : TRANSFERASE
Title : Crystal structure of KDO8P synthase in its binary complex with substrate analog 1-deoxy-A5P
Release Data : 2004-07-13
Compound :
mol_id molecule chains synonym
1 2-dehydro-3-deoxyphosphooctonate aldolase A Phospho-2-dehydro-3-deoxyoctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase, KDO-8-phosphate synthetase, KDO 8-P synthase
ec: 2.5.1.55
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
gene: KDSA
Authors : Vainer, R., Belakhov, V., Rabkin, E., Baasov, T., Adir, N.
Keywords : BETA-ALPHA-BARRELS, LYASE, LIPOPOLYSACCHARIDE, A5P ANALOG, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.36 Å )
Citation :

Crystal structures of Escherichia coli KDO8P synthase complexes reveal the source of catalytic irreversibility.

Vainer, R.,Belakhov, V.,Rabkin, E.  et al.
(2005)  J.Mol.Biol.  351 : 641 - 652

PubMed: 16023668
DOI: 10.1016/j.jmb.2005.06.021

Chain : A
UniProt : P0A715 (KDSA_ECOLI)
Reaction : Phosphoenolpyruvate + D-arabinose 5-phosphate + H(2)O = 3-deoxy-D-manno-octulosonate 8-phosphate + phosphate.