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Ligands
Code Name Style Show Link
ADP Adenosine-5'-diphosphate
MG Magnesium ion
FBP 1,6-di-O-phosphono-beta-D-fructofuranose
Non-standard Residues
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Glycosylation
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Code : 1PFK   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE(PHOSPHOTRANSFERASE)
Title : CRYSTAL STRUCTURE OF THE COMPLEX OF PHOSPHOFRUCTOKINASE FROM ESCHERICHIA COLI WITH ITS REACTION PRODUCTS
Release Data : 1989-01-09
Compound :
mol_id molecule chains
1 PHOSPHOFRUCTOKINASE A,B
ec: 2.7.1.11
Source :
mol_id organism_scientific
1 Escherichia coli  (taxid:562)
cell_line: 293
expression_system_strain: 293
Authors : Shirakihara, Y., Evans, P.R.
Keywords : TRANSFERASE(PHOSPHOTRANSFERASE)
Exp. method : X-RAY DIFFRACTION ( 2.4 Å )
Citation :

Crystal structure of the complex of phosphofructokinase from Escherichia coli with its reaction products.

Shirakihara, Y.,Evans, P.R.
(1988)  J.Mol.Biol.  204 : 973 - 994

PubMed: 2975709
DOI: 10.1016/0022-2836(88)90056-3

Crystal Structure of Unliganded Phosphofructokinase from Escherichia Coli

Rypniewski, W.R.,Evans, P.R.
(1989)  J.Mol.Biol.  207 : 805

Crystallographic Structure of Allosterically Inhibited Phosphofructokinase at 7 Angstroms Resolution

Evans, P.R.,Farrants, G.W.,Lawrence, M.C.
(1986)  J.Mol.Biol.  191 : 713

Nucleotide Sequence and High-Level Expression of the Major Escherichia Coli Phosphofructokinase

Hellinga, H.W.,Evans, P.R.
(1985)  Eur.J.Biochem.  149 : 363

Phosphofructokinase. Structure and Control

Evans, P.R.,Farrants, G.W.,Hudson, P.J.
(1981)  Philos.Trans.R.Soc.London,Ser.B  293 : 53

Structure and Control of Phosphofructokinase from Bacillus Stearothermophilus

Evans, P.R.,Hudson, P.J.
(1979)  Nature  279 : 500

The Three-Dimensional Structure of Phosphofructokinase from Bacillus Stearothermophilus

Evans, P.R.,Hudson, P.J.
(1978)  Proc.FEBS Meet.  52 : 349

Chain : A, B
UniProt : P0A796 (PFKA_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+) 2.7.1.11 HAMAP- Rule:MF_00339, PubMed:2953977, PubMed:3158524
-
ATP + D-sedoheptulose 7-phosphate = ADP + D-sedoheptulose 1,7- bisphosphate + H(+) - PubMed:19756045
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