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Ligands
Code Name Style Show Link
ACY Acetic acid
DPM 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1h-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1h-pyrrol-3-yl]propanoic acid
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Code : 1PDA   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : STRUCTURE OF PORPHOBILINOGEN DEAMINASE REVEALS A FLEXIBLE MULTIDOMAIN POLYMERASE WITH A SINGLE CATALYTIC SITE
Release Data : 1993-10-31
Compound :
mol_id molecule chains
1 PORPHOBILINOGEN DEAMINASE A
ec: 2.5.1.61
Source :
mol_id organism_scientific
1 Escherichia coli  (taxid:562)
Authors : Louie, G.V., Brownlie, P.D., Lambert, R., Cooper, J.B., Blundell, T.L., Wood, S.P., Warren, M.J., Woodcock, S.C., Jordan, P.M.
Keywords : PORPHYRIN, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.76 Å )
Citation :

Structure of porphobilinogen deaminase reveals a flexible multidomain polymerase with a single catalytic site.

Louie, G.V.,Brownlie, P.D.,Lambert, R.  et al.
(1992)  Nature  359 : 33 - 39

PubMed: 1522882
DOI: 10.1038/359033a0

Chain : A
UniProt : P06983 (HEM3_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+) 2.5.1.61 PubMed:3052434
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