Brand  (β version)

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Ligands
Code Name Link
NHE 2-[N-cyclohexylamino]ethane sulfonic acid
Code : 1P7I
Header : DNA BINDING PROTEIN
Title : CRYSTAL STRUCTURE OF ENGRAILED HOMEODOMAIN MUTANT K52A
Release Data : 2003-10-14
Compound :
mol_id molecule chains
1 Segmentation polarity homeobox protein engrailed A,B,C,D
fragment: Homeodomain
mutation: K52A
Source :
mol_id organism_scientific organism_common expression_system
1 Drosophila melanogaster  (taxid:7227) Fruit fly Escherichia coli  (taxid:562)
gene: EN
expression_system_strain: C41
expression_system_vector_type: PLASMID
expression_system_plasmid: pET3a
Authors : Stollar, E.J., Mayor, U., Lovell, S.C., Federici, L., Freund, S.M., Fersht, A.R., Luisi, B.F.
Keywords : DNA Binding Protein
Exp. method : X-RAY DIFFRACTION ( 2.10 Å )
Citation :

Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS

Stollar, E.J.,Mayor, U.,Lovell, S.C.  et al.
(2003)  J.Biol.Chem.  278 : 43699 - 43708

PubMed: 12923178
DOI: 10.1074/jbc.M308029200

Structural studies of the engrailed homeodomain

Clarke, N.D.,Kissinger, C.R.,Desjarlais, J.  et al.
(1994)  Protein Sci.  3 : 1779 - 1787

Engrailed Homeodomain-DNA Complex at 2.2 A Resolution: A Detailed View of the Interface and Comparison with other Engrailed Structures

Fraenkel, E.,Rould, M.A.,Chambers, K.A.  et al.
(1998)  J.Mol.Biol.  284 : 351 - 361

DOI: 10.1006/jmbi.1998.2147

Chain : A, B, C, D
UniProt : P02836 (HMEN_DROME)
Reaction : -