PDB ID: 1P6M
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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ACT | Acetate ion | PoSSuM | |||
CAC | Cacodylate ion | PoSSuM | |||
DP3 | N-{(4s)-4-amino-5-[(2-aminoethyl)amino]pentyl}-N'-nitroguanidine | PoSSuM | |||
GOL | Glycerol | PoSSuM | |||
H4B | 5,6,7,8-tetrahydrobiopterin | PoSSuM | |||
HEM | Protoporphyrin ix containing Fe | PoSSuM | |||
ZN | Zinc ion | PoSSuM |
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Download interaction data: 1P6M
Structure summary
Code : | 1P6M PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | Bovine endothelial NOS heme domain with (4S)-N-(4-amino-5-[aminoethyl]aminopentyl)-N'-nitroguanidine bound | ||||||||||||
Release Data : | 2004-01-13 | ||||||||||||
Compound : |
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Source : |
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Authors : | Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L. | ||||||||||||
Keywords : | nitric oxide synthase, oxidoreductase, heme-enzyme | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.27 Å ) | ||||||||||||
Citation : |
Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Flinspach, M.L.,Li, H.,Jamal, J.
et al.
PubMed: 14718923 CRYSTAL STRUCTURE OF CONSTITUTIVE ENDOTHELIAL NITRIC OXIDE SYNTHASE: A PARADIGM FOR PTERIN FUNCTION INVOLVING A NOVEL METAL CENTER
Raman, C.S.,Li, H.,Martasek, P.
et al.
The novel binding mode of N-alkyl-N'-hydroxyguanidine to neuronal nitric oxide synthase provides mechanistic insights into NO biosynthesis
Li, H.,Shimizu, H.,Flinspach, M.
et al.
DOI: 10.1021/bi020417c |
Reaction
Chain : | A, B | ||||||||
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UniProt : | P29473 (NOS3_BOVIN) | ||||||||
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