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Ligands
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KAI 3-(carboxymethyl)-4-isopropenylproline
Non-standard Residues
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Glycosylation
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Code : 1P1N   PDBj   RCSB PDB   PDBe
Header : MEMBRANE PROTEIN
Title : GluR2 Ligand Binding Core (S1S2J) Mutant L650T in Complex with Kainate
Release Data : 2003-06-10
Compound :
mol_id molecule chains synonym
1 Glutamate receptor 2 A GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2
fragment: ligand binding core (S1S2J)
mutation: L138T
Source :
mol_id organism_scientific organism_common expression_system
1 Rattus norvegicus  (taxid:10116) Norway rat Escherichia coli BL21  (taxid:511693)
gene: GRIA2 OR GLUR2
expression_system_strain: BL21
expression_system_vector_type: PLASMID
expression_system_plasmid: pETGQ
Authors : Armstrong, N., Mayer, M.L., Gouaux, E.
Keywords : ionotropic glutamate receptor, MEMBRANE PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.6 Å )
Citation :

Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.

Armstrong, N.,Mayer, M.,Gouaux, E.
(2003)  Proc.Natl.Acad.Sci.USA  100 : 5736 - 5741

PubMed: 12730367
DOI: 10.1073/pnas.1037393100

Chain : A
UniProt : P19491 (GRIA2_RAT)
Reaction : -