PDB ID: 1OHK
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
---|---|---|---|---|---|
COP | N-(4-carboxy-4-{4-[(2,4-diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-butyl)-phthalamic acid | PoSSuM | |||
NDP | Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate | PoSSuM |
Code | Name | Show |
---|
Code | Name | Emphasize |
---|
Code | Name | Show |
---|
Download interaction data: 1OHK
Structure summary
Code : | 1OHK PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | OXIDOREDUCTASE | ||||||||||||
Title : | HUMAN DIHYDROFOLATE REDUCTASE, ORTHORHOMBIC (P21 21 21) CRYSTAL FORM | ||||||||||||
Release Data : | 1998-05-27 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Cody, V., Galitsky, N., Luft, J.R., Pangborn, W. | ||||||||||||
Keywords : | OXIDOREDUCTASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.5 Å ) | ||||||||||||
Citation : |
Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523.
Cody, V.,Galitsky, N.,Luft, J.R.
et al.
PubMed: 9374868 Methotrexate-Resistant Variants of Human Dihydrofolate Reductase with Substitutions of Leucine 22. Kinetics, Crystallography, and Potential as Selectable Markers
Lewis, W.S.,Cody, V.,Galitsky, N.
et al.
Methotrexate-Resistant Variants of Human Dihydrofolate Reductase. Effects of Phe31 Substitutions
Chunduru, S.K.,Cody, V.,Luft, J.R.
et al.
Crystal Structure Determination at 2.3 A of Recombinant Human Dihydrofolate Reductase Ternary Complex with Nadph and Methotrexate-Gamma-Tetrazole
Cody, V.,Luft, J.R.,Ciszak, E.
et al.
|
Reaction
Chain : | A | ||||||||
---|---|---|---|---|---|---|---|---|---|
UniProt : | P00374 (DYR_HUMAN) | ||||||||
|