PDB ID: 1O3H
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Structure summary
Code : | 1O3H PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors | ||||||||||||
Release Data : | 2003-09-02 | ||||||||||||
Compound : |
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Source : |
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Authors : | Katz, B.A., Elrod, K., Verner, E., Mackman, R.L., Luong, C., Shrader, W.D., Sendzik, M., Spencer, J.R., Sprengeler, P.A., Kolesnikov, A., Tai, V.W., Hui, H.C., Breitenbucher, J.G., Allen, D., Janc, J.W. | ||||||||||||
Keywords : | serine protease, short hydrogen bond, inhibition mechanism, shift of pKa, trypsin, thrombin, urokinase, factor Xa, hydrolase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.53 Å ) | ||||||||||||
Citation : |
Elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease inhibitors.
Katz, B.A.,Elrod, K.,Verner, E.
et al.
PubMed: 12742021 |
Reaction
Chain : | A | ||||||||
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UniProt : | P00760 (TRY1_BOVIN) | ||||||||
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