Brand  (β version)

PDB ID: 1NYX

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Ligands
Code Name Style Show Link
DRF (2s)-2-ethoxy-3-{4-[2-(10h-phenoxazin-10-yl)ethoxy]phenyl}propanoic acid PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1NYX   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION
Title : Ligand binding domain of the human peroxisome proliferator activated receptor gamma in complex with an agonist
Release Data : 2003-07-15
Compound :
mol_id molecule chains
1 peroxisome proliferator activated receptor gamma A,B
fragment: Ligand binding domain
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
expression_system_vector_type: plasmid
expression_system_plasmid: pGEX-3X
Authors : Ebdrup, S., Pettersson, I., Rasmussen, H.B., Deussen, H.-J., Frost Jensen, A., Mortensen, S.B., Fleckner, J., Pridal, L., Nygaard, L., Sauerberg, P.
Keywords : PPAR, nuclear receptor, Transcription, gene regulation, agonist complex
Exp. method : X-RAY DIFFRACTION ( 2.65 Å )
Citation :

Synthesis and biological and structural characterization of the dual-acting peroxisome proliferator-activated receptor alpha/gamma agonist ragaglitazar

Ebdrup, S.,Pettersson, I.,Rasmussen, H.B.  et al.
(2003)  J.MED.CHEM.  46 : 1306 - 1317

PubMed: 12672231
DOI: 10.1021/jm021027r

Reaction

Chain : A, B
UniProt : P37231 (PPARG_HUMAN)
Reaction : -