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Ligands
Code Name Style Show Link
CO Cobalt (II) ion
G Guanosine-5'-monophosphate
Non-standard Residues
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Glycosylation
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Code : 1NYI   PDBj   RCSB PDB   PDBe
Header : RNA
Title : Crosslinked Hammerhead Ribozyme Initial State
Release Data : 2004-02-24
Compound :
mol_id molecule chains
1 5'-R(P*GP*UP*GP*GP*UP*CP*UP*GP*AP*UP*GP*AP*GP*GP*CP*C)-3' A
mol_id molecule chains
2 5'-R(*GP*CP*CP*GP*AP*AP*AP*CP*UP*CP*GP*UP*AP*AP*GP*AP*GP*UP*CP*AP*CP*CP*AP*C)-3' B
Source :
mol_id organism_scientific
1
synthetic: yes
mol_id organism_scientific
2
synthetic: yes
Authors : Dunham, C.M., Murray, J.B., Scott, W.G.
Keywords : Hammerhead Ribozyme crosslink conformational change, RNA
Exp. method : X-RAY DIFFRACTION ( 2.85 Å )
Citation :

A helical twist-induced conformational switch activates cleavage in the hammerhead ribozyme.

Dunham, C.M.,Murray, J.B.,Scott, W.G.
(2003)  J.Mol.Biol.  332 : 327 - 336

PubMed: 12948485
DOI: 10.1016/S0022-2836(03)00843-X