Het-PDB Navi2 (PDB: 1NQ2)

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Ligands
Code	Name	Link
NA	Sodium ion	PoSSuM
4HY	[4-(4-hydroxy-3-iodo-phenoxy)-3,5-diiodo-phenyl]-acetic acid	PoSSuM
ARS	Arsenic	PoSSuM

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Download interaction data: 1NQ2

Code :

1NQ2 PDBj RCSB PDB PDBe

Header :

HORMONE/GROWTH FACTOR RECEPTOR

Title :

Two RTH Mutants with Impaired Hormone Binding

Release Data :

2003-04-15

Compound :

mol_id	molecule	chains
1	Thyroid hormone receptor beta-1	A
	fragment: LIGAND BINDING DOMAIN

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: THRB OR NR1A2 OR ERBA2 OR THR1 expression_system_strain: BL21 DE3 PLYSS expression_system_vector_type: PLASMID expression_system_plasmid: PET28A

Authors :

Huber, B.R., Sandler, B., West, B.L., Cunha-Lima, S.T., Nguyen, H.T., Apriletti, J.W., Baxter, J.D., Fletterick, R.J.

Keywords :

ALPHA HELICAL, LIGAND BINDING DOMAIN, HORMONE-GROWTH FACTOR RECEPTOR COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 2.4 Å )

Citation :

Two resistance to thyroid hormone mutants with impaired hormone binding

Huber, B.R.,Sandler, B.,West, B.L. et al.
(2003) Mol.Endocrinol. 17 : 643 - 652

PDB ID: 1NQ2