Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
13P 1,3-dihydroxyacetonephosphate
Modified Residues
Code Name Link
FTR Fluorotryptophane
Code : 1NF0
Header : ISOMERASE
Title : Triosephosphate Isomerase in Complex with DHAP
Release Data : 2003-01-07
Compound :
mol_id molecule chains synonym
1 triosephosphate isomerase A,B TIM
ec: 5.3.1.1
mutation: W90Y, W157F, W168(FTR)
Source :
mol_id organism_scientific organism_common expression_system
1 Saccharomyces cerevisiae  (taxid:4932) Baker's yeast Escherichia coli  (taxid:562)
gene: TPI1
expression_system_strain: JA300
expression_system_vector_type: plasmid
expression_system_plasmid: PKK223-3
Authors : Jogl, G., Rozovsky, S., McDermott, A.E., Tong, L.
Keywords : yeast, triosephosphate isomerase, DHAP, dihydroxyacetone phosphate, michaelis complex, ISOMERASE
Exp. method : X-RAY DIFFRACTION ( 1.60 Å )
Citation :

Optimal alignment for enzymatic proton transfer: Structure of the Michaelis complex of triosephosphate isomerase at 1.2-A resolution

Jogl, G.,Rozovsky, S.,McDermott, A.E.  et al.
(2003)  Proc.Natl.Acad.Sci.USA  100 : 50 - 55

PubMed: 12509510
DOI: 10.1073/pnas.0233793100

Chain : A, B
UniProt : P00942 (TPIS_YEAST)
Reaction : D-glyceraldehyde 3-phosphate = glycerone phosphate.