Brand  (β version)

PDB ID: 1N83

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Ligands
Code Name Style Show Link
CLR Cholesterol PoSSuM
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Glycosylation
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Structure summary

Code : 1N83   PDBj   RCSB PDB   PDBe
Header : LIPID BINDING PROTEIN
Title : Crystal Structure of the complex between the Orphan Nuclear Hormone Receptor ROR(alpha)-LBD and Cholesterol
Release Data : 2002-12-11
Compound :
mol_id molecule chains synonym
1 Nuclear receptor ROR-alpha A nuclear receptor RZR-alpha
fragment: Ligand Binding Domain, residues 304-556
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Spodoptera frugiperda  (taxid:7108)
expression_system_common: Fall armyworm
expression_system_strain: Sf9
expression_system_vector_type: Virus
Authors : Kallen, J.A., Schlaeppi, J.M., Bitsch, F., Geisse, S., Geiser, M., Delhon, I., Fournier, B.
Keywords : three-layered alpha helical sandwich, receptor, transcription regulation, nuclear protein, DNA binding, LIPID BINDING PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.63 Å )
Citation :

X-ray Structure of hROR(alpha) LBD at 1.63A: Structural and Functional data that Cholesterol or a Cholesterol derivative is the natural ligand of ROR(alpha)

Kallen, J.A.,Schlaeppi, J.M.,Bitsch, F.  et al.
(2002)  Structure  10 : 1697 - 1702

PubMed: 12467577
DOI: 10.1016/S0969-2126(02)00912-7

Reaction

Chain : A
UniProt : P35398 (RORA_HUMAN)
Reaction : -