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Ligands
Code Name Style Show Link
CXS 3-cyclohexyl-1-propylsulfonic acid
GOL Glycerol
K Potassium ion
SO4 Sulfate ion
Non-standard Residues
Code Name Show
ORN L-ornithine
Glycosylation
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Modification
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Code : 1N0X   PDBj   RCSB PDB   PDBe
Header : IMMUNE SYSTEM
Title : Crystal Structure of a Broadly Neutralizing Anti-HIV-1 Antibody in Complex with a Peptide Mimotope
Release Data : 2004-04-13
Compound :
mol_id molecule chains synonym
1 IMMUNOGLOBULIN LIGHT CHAIN L,M IGG
fragment: UNP residues 132-239
mol_id molecule chains synonym
2 IMMUNOGLOBULIN HEAVY CHAIN H,K IGG,Immunoglobulin gamma-1 heavy chain NIE
fragment: UNP residues 117-222
mol_id molecule chains
3 B2.1 peptide P,R
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Cricetulus griseus  (taxid:10029)
expression_system_common: Chinese hamster
expression_system_strain: CHO K1
expression_system_cell: ovary cells
mol_id organism_scientific organism_common expression_system
2 Homo sapiens  (taxid:9606) Human Cricetulus griseus  (taxid:10029)
expression_system_common: Chinese hamster
expression_system_strain: CHO K1
expression_system_cell: ovary cells
mol_id organism_scientific
3 Synthetic construct  (taxid:32630)
synthetic: yes
other_details: selected from phage display peptide library, then chemically synthesized.
Authors : Saphire, E.O., Montero, M., Menendez, A., Irving, M.B., Zwick, M.B., Parren, P.W.H.I., Burton, D.R., Scott, J.K., Wilson, I.A.
Keywords : antibody-peptide complex, peptide dimer, IMMUNE SYSTEM
Exp. method : X-RAY DIFFRACTION ( 1.8 Å )
Citation :

Crystal Structure of a Broadly Neutralizing Anti-HIV-1 Antibody in Complex with a Peptide Mimotope

Saphire, E.O.,Montero, M.,Menendez, A.  et al.
To be Published 

Chain : L, M
UniProt : Q8TCD0 (Q8TCD0_HUMAN)
Reaction : -
Chain : H, K
UniProt : P0DOX5 (IGG1_HUMAN)
Reaction : -