Het-PDB Navi2 (PDB: 1MV9)

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Ligands
Code	Name		Style	Show	Link
HXA	Docosa-4,7,10,13,16,19-hexaenoic acid				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1MV9

Code :

1MV9 PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

Crystal Structure of the human RXR alpha ligand binding domain bound to the eicosanoid DHA (Docosa Hexaenoic Acid) and a coactivator peptide

Release Data :

2002-10-16

Compound :

mol_id	molecule	chains	synonym
1	RXR retinoid X receptor	A	Retinoic acid receptor RXR-alpha
	fragment: ligand binding domain(residues 223-462)

mol_id	molecule	chains	synonym
2	Nuclear receptor coactivator 2	B	GRIP1
	fragment: NR box

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli BL21(DE3) (taxid:469008)
	expression_system_strain: BL21 (DE3) expression_system_vector_type: PLASMID expression_system_plasmid: pET-15b

mol_id	organism_scientific
2
	synthetic: yes other_details: a synthetic peptide of a coactivator protein

Authors :

Egea, P.F., Mitschler, A., Moras, D.

Keywords :

Transcription regulation, Nuclear protein, Transcription

Exp. method :

X-RAY DIFFRACTION ( 1.9 Å )

Citation :

Molecular Recognition of Agonist Ligands by RXRs

Egea, P.F.,Mitschler, A.,Moras, D.
(2002) MOL.ENDOCRINOL. 16 : 987 - 997

PDB ID: 1MV9