Het-PDB Navi2 (PDB: 1MRL)

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Ligands
Code	Name		Style	Show	Link
DOL	5-(2-diethylamino-ethanesulfonyl)-21-hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triaza-tricyclo[23.2.1.00,255]octacosa-1(27),12,17,19,25(28)-pentaene-2,8,14,23-tetraone				PoSSuM

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Download interaction data: 1MRL

Code :

1MRL PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Crystal structure of streptogramin A acetyltransferase with dalfopristin

Release Data :

2003-08-26

Compound :

mol_id	molecule	chains
1	Streptogramin A acetyltransferase	A,B,C
	ec: 2.3.1.-

Source :

mol_id	organism_scientific	expression_system
1	Enterococcus faecium (taxid:1352)	Escherichia coli (taxid:562)
	expression_system_strain: JM101 expression_system_vector_type: plasmid expression_system_plasmid: pUC18

Authors :

Kehoe, L.E., Snidwongse, J., Courvalin, P., Rafferty, J.B., Murray, I.A.

Keywords :

left-handed parallel beta-helix domain, TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 2.80 Å )

Citation :

Structural Basis of Synercid (Quinupristin-Dalfopristin) Resistance in Gram-positive Bacterial Pathogens

Kehoe, L.E.,Snidwongse, J.,Courvalin, P. et al.
(2003) J.Biol.Chem. 278 : 29963 - 29970

PDB ID: 1MRL