Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
DCP 2'-deoxycytidine-5'-triphosphate
MG Magnesium ion
NA Sodium ion
Modified Residues
Code Name Link
8OG 8-oxo-2'-deoxy-guanosine-5'-monophosphate
DOC 2',3'-dideoxycytidine-5'-monophosphate
Code : 1MQ3
Header : TRANSFERASE/DNA
Title : Human DNA Polymerase Beta Complexed With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine Template Paired with dCTP
Release Data : 2003-01-28
Compound :
mol_id molecule chains
1 5'-D(*CP*CP*GP*AP*CP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3' T
mol_id molecule chains
2 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3' P
mol_id molecule chains
3 5'-D(P*GP*TP*CP*GP*G)-3' D
mol_id molecule chains
4 DNA POLYMERASE BETA A
ec: 2.7.7.7
Source :
mol_id organism_scientific
1
synthetic: yes
mol_id organism_scientific
2
synthetic: yes
mol_id organism_scientific
3
synthetic: yes
mol_id organism_scientific organism_common expression_system
4 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
Authors : Krahn, J.M., Beard, W.A., Miller, H., Grollman, A.P., Wilson, S.H.
Keywords : TRANSFERASE, DNA, TRANSFERASE-DNA COMPLEX
Exp. method : X-RAY DIFFRACTION ( 2.8 Å )
Citation :

Structure of DNA Polymerase beta with the Mutagenic DNA Lesion 8-oxodeoxyguanine Reveals Structural Insights into its Coding Potential

Krahn, J.M.,Beard, W.A.,Miller, H.  et al.
(2003)  Structure  11 : 121 - 127

PubMed: 12517346
DOI: 10.1016/S0969-2126(02)00930-9

Chain : A
UniProt : P06746 (DPOLB_HUMAN)
Reaction : Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).