Brand  (β version)

PDB ID: 1MK6

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Ligands
Code Name Style Show Link
AFN 8,9-dihydro-9-hydroxy-aflatoxin b1 PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1MK6   PDBj   RCSB PDB   PDBe
Header : DNA
Title : SOLUTION STRUCTURE OF THE 8,9-DIHYDRO-8-(N7-GUANYL)-9-HYDROXY-AFLATOXIN B1 ADDUCT MISPAIRED WITH DEOXYADENOSINE
Release Data : 2002-10-16
Compound :
mol_id molecule chains
1 5'-D(*AP*CP*AP*TP*CP*GP*AP*TP*CP*T)-3' A
mol_id molecule chains
2 5'-D(*AP*GP*AP*TP*AP*GP*AP*TP*GP*T)-3' B
Source :
mol_id organism_scientific
1 Synthetic construct  (taxid:32630)
synthetic: yes
mol_id organism_scientific
2 Synthetic construct  (taxid:32630)
synthetic: yes
Authors : Giri, I., Johnston, D.S., Stone, M.P.
Keywords : AFLATOXIN B1- Guanine Adduct Opposite an Adenine, mimicking GA Transition, DNA
Exp. method : SOLUTION NMR
Citation :

MISPAIRING OF THE 8,9-DIHYDRO-8-(N7-GUANYL)-9-HYDROXY-AFLATOXIN B1 ADDUCT WITH DEOXYADENOSINE RESULTS IN EXTRUSION OF THE MISMATCHED DA TOWARD THE MAJOR GROOVE

Giri, I.,Johnston, D.S.,Stone, M.P.
(2002)  Biochemistry  41 : 5462 - 5472

PubMed: 11969407
DOI: 10.1021/bi012116t