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Ligands
Code Name Style Show Link
MG Magnesium ion
TTP Thymidine-5'-triphosphate
Non-standard Residues
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MSE Selenomethionine
Glycosylation
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Modification
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Code : 1MC3   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : CRYSTAL STRUCTURE OF RFFH
Release Data : 2002-11-20
Compound :
mol_id molecule chains synonym
1 GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE A,B rFFH, dTDP-glucose synthase, dTDP-glucose pyrophosphorylase
ec: 2.7.7.24
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
expression_system_strain: DL41
Authors : Sivaraman, J., Sauve, V., Matte, A., Cygler, M., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Keywords : Glucose-1-phosphate thymidylytransferase, rffH, Montreal-Kingston Bacterial Structural Genomics Initiative, BSGI, Structural Genomics, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.6 Å )
Citation :

Crystal Structure of Escherichia coli Glucose-1-Phosphate Thymidylyltransferase (RffH) Complexed with dTTP and Mg2+

Sivaraman, J.,Sauve, V.,Matte, A.  et al.
(2002)  J.BIOL.CHEM.  277 : 44214 - 44219

PubMed: 12171937
DOI: 10.1074/jbc.M206932200

Chain : A, B
UniProt : P61887 (RMLA2_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate + dTDP-alpha-D-glucose 2.7.7.24 PubMed:7559340
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