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Ligands
Code Name Style Show Link
CYS Cysteine
NDP Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate
Non-standard Residues
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Glycosylation
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Code : 1MB4   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of aspartate semialdehyde dehydrogenase from vibrio cholerae with NADP and S-methyl-L-cysteine sulfoxide
Release Data : 2003-01-07
Compound :
mol_id molecule chains
1 Aspartate-Semialdehyde Dehydrogenase A,B
ec: 1.2.1.11
Source :
mol_id organism_scientific expression_system
1 Vibrio cholerae  (taxid:666) Escherichia coli BL21(DE3)  (taxid:469008)
gene: asd
expression_system_strain: BL21DE3
expression_system_vector_type: Plasmid
expression_system_plasmid: PET41
Authors : Blanco, J., Moore, R.A., Kabaleeswaran, V., Viola, R.E.
Keywords : enzyme, aspartate-semialdehyde dehydrogenase, complex, vibrio cholerae, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 1.84 Å )
Citation :

A structural Basis for the Mechanism of Aspartate-beta-semialdehyde Dehydrogenase from Vibrio Cholerae

Blanco, J.,Moore, R.A.,Kabaleeswaran, V.  et al.
(2003)  Protein Sci.  12 : 27 - 33

PubMed: 12493825
DOI: 10.1110/ps.0230803

Chain : A, B
UniProt : Q9KQG2 (DHAS1_VIBCH)
Reaction: EC: Evidence:
Physiological Direction:
L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho- L-aspartate + H(+) + NADPH 1.2.1.11 PubMed:12071715
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