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Ligands
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DAO Lauric acid
Non-standard Residues
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Glycosylation
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Code : 1M7W   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION FACTOR
Title : HNF4a ligand binding domain with bound fatty acid
Release Data : 2003-07-01
Compound :
mol_id molecule chains synonym
1 Hepatocyte nuclear factor 4-alpha A,B,C,D HNF-4-alpha, Transcription factor HNF-4, Transcription factor 14
fragment: Residues 133-382
Source :
mol_id organism_scientific organism_common expression_system
1 Rattus rattus  (taxid:10117) Black rat Escherichia coli BL21(DE3)  (taxid:469008)
gene: HNF4a
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pet28
Authors : Dhe-Paganon, S., Duda, K., Iwamoto, M., Chi, Y.I., Shoelson, S.E.
Keywords : Transcription factor
Exp. method : X-RAY DIFFRACTION ( 2.8 Å )
Citation :

Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand

Dhe-Paganon, S.,Duda, K.,Iwamoto, M.  et al.
(2002)  J.Biol.Chem.  277 : 37973 - 37976

PubMed: 12193589
DOI: 10.1074/jbc.C200420200

Chain : A, B, C, D
UniProt : P22449 (HNF4A_RAT)
Reaction : -