Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
EDO 1,2-ethanediol
Modified Residues
Code Name Link
0QE Chloromethane
ACE Acetyl group
Code : 1M72
Header : HYDROLASE/HYDROLASE INHIBITOR
Title : Crystal Structure of Caspase-1 from Spodoptera frugiperda
Release Data : 2004-01-20
Compound :
mol_id molecule chains
1 Caspase-1 A,B,C
ec: 3.4.22.36
mol_id molecule chains
2 Ace-Asp-Glu-Val-Asp-chloromethylketone D,E,F
Source :
mol_id organism_scientific organism_common expression_system
1 Spodoptera frugiperda  (taxid:7108) Fall armyworm Escherichia coli BL21  (taxid:511693)
expression_system_strain: BL21
expression_system_vector_type: plasmid
expression_system_plasmid: pET22b
mol_id organism_scientific
2
synthetic: yes
other_details: The peptide is a synthetic tetrapeptide inhibitor.
Authors : Forsyth, C.M., Lemongello, D., Friesen, P.D., Fisher, A.J.
Keywords : CASPASE, CYSTEINE PROTEASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Exp. method : X-RAY DIFFRACTION ( 2.30 Å )
Citation :

Crystal structure of an invertebrate caspase.

Forsyth, C.M.,Lemongello, D.,LaCount, D.J.  et al.
(2004)  J.Biol.Chem.  279 : 7001 - 7008

PubMed: 14645217
DOI: 10.1074/jbc.M312472200

Chain : A, B, C
UniProt : P89116 (CASP1_SPOFR)
Reaction : -