Brand  (β version)

PDB ID: 1LRL

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Ligands
Code Name Style Show Link
NA Sodium ion PoSSuM
NAD Nicotinamide-adenine-dinucleotide PoSSuM
PGE Triethylene glycol PoSSuM
UPG Uridine-5'-diphosphate-glucose PoSSuM
Non-standard Residues
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Structure summary

Code : 1LRL   PDBj   RCSB PDB   PDBe
Header : ISOMERASE
Title : Crystal Structure of UDP-Galactose 4-Epimerase Mutant Y299C Complexed with UDP-Glucose
Release Data : 2002-07-26
Compound :
mol_id molecule chains synonym
1 UDP-glucose 4-epimerase A UDP-galactose-4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; UDPglucose 4-epimerase
ec: 5.1.3.2
mutation: Y299C
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
gene: GALE
expression_system_variant: Bl21(DE3)pLysS
expression_system_vector_type: plasmid
expression_system_plasmid: pTZSynE
Authors : Thoden, J.B., Henderson, J.M., Fridovich-Keil, J.L., Holden, H.M.
Keywords : epimerase, short chain dehydrogenase, galactosemia, ISOMERASE
Exp. method : X-RAY DIFFRACTION ( 1.80 Å )
Citation :

Structural analysis of the Y299C mutant of Escherichia coli UDP-galactose 4-epimerase. Teaching an old dog new tricks.

Thoden, J.B.,Henderson, J.M.,Fridovich-Keil, J.L.  et al.
(2002)  J.Biol.Chem.  277 : 27528 - 27534

PubMed: 12019271
DOI: 10.1074/jbc.M204413200

Reaction

Chain : A
UniProt : P09147 (GALE_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
UDP-alpha-D-glucose = UDP-alpha-D-galactose 5.1.3.2 PubMed:14235524
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