Brand  (β version)

PDB ID: 1LPH

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Ligands
Code Name Style Show Link
ZN Zinc ion PoSSuM
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Structure summary

Code : 1LPH   PDBj   RCSB PDB   PDBe
Header : HORMONE
Title : LYS(B28)PRO(B29)-HUMAN INSULIN
Release Data : 1996-06-20
Compound :
mol_id molecule chains synonym
1 INSULIN A,C LYS(B28)PRO(B29)-HUMAN INSULIN
mutation: CHAIN B, D, P28K, K29P
mol_id molecule chains synonym
2 INSULIN B,D LYS(B28)PRO(B29)-HUMAN INSULIN
mutation: CHAIN B, D, P28K, K29P
Source :
mol_id organism_scientific organism_common
1 Homo sapiens  (taxid:9606) Human
mol_id organism_scientific organism_common
2 Homo sapiens  (taxid:9606) Human
Authors : Ciszak, E., Beals, J.M., Frank, B.H., Baker, J.C., Carter, N.D., Smith, G.D.
Keywords : INSULIN ANALOGUE, HORMONE, GLUCOSE METABOLISM
Exp. method : X-RAY DIFFRACTION ( 2.3 Å )
Citation :

Role of C-terminal B-chain residues in insulin assembly: the structure of hexameric LysB28ProB29-human insulin.

Ciszak, E.,Beals, J.M.,Frank, B.H.  et al.
(1995)  Structure  3 : 615 - 622

PubMed: 8590022
DOI: 10.1016/S0969-2126(01)00195-2

The Structure of a Complex of Hexameric Insulin and 4'-Hydroxyacetanilide

Smith, G.D.,Ciszak, E.
(1994)  Proc.Natl.Acad.Sci.USA  91 : 8851

Crystallographic Evidence for Dual Coordination Around Zinc in the T3R3 Human Insulin Hexamer

Ciszak, E.,Smith, G.D.
(1994)  Biochemistry  33 : 1512

Structural Stability in the 4-Zinc Human Insulin Hexamer

Smith, G.D.,Swenson, D.C.,Dodson, E.J.  et al.
(1984)  Proc.Natl.Acad.Sci.USA  81 : 7093

Reaction

Chain : B, D
UniProt : P01308 (INS_HUMAN)
Reaction : -