Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
U Uridine-5'-monophosphate
Modified Residues
Code Name Link
CSO S-hydroxycysteine
Code : 1LOQ
Header : LYASE
Title : Crystal structure of orotidine monophosphate decarboxylase complexed with product UMP
Release Data : 2002-08-07
Compound :
mol_id molecule chains synonym
1 orotidine 5'-monophosphate decarboxylase A OMP decarboxylase, ompdecase, ompdcase
ec: 4.1.1.23
Source :
mol_id organism_scientific expression_system
1 Archaea  (taxid:2157) Escherichia coli  (taxid:562)
strain: delta H
expression_system_vector_type: plasmid
expression_system_plasmid: pET15b
Authors : Wu, N., Pai, E.F.
Keywords : TIM barrel, Lyase
Exp. method : X-RAY DIFFRACTION ( 1.50 Å )
Citation :

Crystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylase.

Wu, N.,Pai, E.F.
(2002)  J.Biol.Chem.  277 : 28080 - 28087

PubMed: 12011084
DOI: 10.1074/jbc.M202362200

Chain : A
UniProt : O26232 (PYRF_METTH)
Reaction : Orotidine 5'-phosphate = UMP + CO(2).