Het-PDB Navi2 (PDB: 1LKE)

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Ligands
Code	Name		Style	Show	Link
DOG	Digoxigenin				PoSSuM

Non-standard Residues
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Glycosylation
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Modification
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Download interaction data: 1LKE

Code :

1LKE PDBj RCSB PDB PDBe

Header :

LIGAND BINDING PROTEIN

Title :

ENGINEERED LIPOCALIN DIGA16 IN COMPLEX WITH DIGOXIGENIN

Release Data :

2003-06-17

Compound :

mol_id	molecule	chains	synonym
1	DigA16	A	BILIN BINDING PROTEIN, BBP, DIGA16 ANTICALIN
	mutation: N1D, N21G, E28Q, K31A, N34D, S35H, V36I, E37T, N48R, H60S, I69S, K87S, L88Y, Y90I, K95Q, N97G, Y114F, K116S, Q125M, F127L, K135M other_details: GENETICALLY ENGINEERED VARIANT OF BILIN BINDING PROTEIN

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Pieris brassicae (taxid:7116)	Large cabbage white	Escherichia coli (taxid:562)
	expression_system_strain: jm83 expression_system_vector_type: plasmid expression_system_plasmid: pbbp21-diga16

Authors :

Korndoerfer, I.P., Skerra, A.

Keywords :

PIERIS BRASSICAE, LIPOCALIN, ANTICALIN, GENETICAL ENGINEERING, DIGOXIGENIN, LIGAND BINDING PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 1.9 Å )

Citation :

Structural mechanism of specific ligand recognition by a lipocalin tailored for the complexation of digoxigenin.

Korndoerfer, I.P.,Schlehuber, S.,Skerra, A.
(2003) J.Mol.Biol. 330 : 385 - 396

A Novel Type of Receptor Protein, based on the Lipocalin Scaffold, with Specificity for Digoxigenin

Schlehuber, S.,Beste, G.,Skerra, A.
(2000) J.Mol.Biol. 297 : 1105 - 1120

Small Antibody-like Proteins with Prescribed Ligand Specificities Derived from the Lipocalin Fold.

Beste, G.,Schmidt, F.S.,Stibora, T. et al.
(1999) Proc.Natl.Acad.Sci.USA 96 : 1898 - 1903

PDB ID: 1LKE