Brand  (β version)

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centroid:
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Ligands
Code Name Link
AU Gold ion
Code : 1LJ2
Header : Viral protein/ translation
Title : Recognition of eIF4G by Rotavirus NSP3 reveals a basis for mRNA circularization
Release Data : 2002-07-05
Compound :
mol_id molecule chains synonym
1 NONSTRUCTURAL RNA-BINDING PROTEIN 34 A,B NSP3-C; NS34; NCVP4; non-structural protein NCVP4
fragment: C-terminal domain
mutation: C306S C314S
mol_id molecule chains synonym
2 eukaryotic protein synthesis initiation factor C,D eIF4GI
fragment: residues 132-159 of AAC82471
Source :
mol_id organism_scientific expression_system
1 Simian rotavirus A/SA11  (taxid:10923) Escherichia coli  (taxid:562)
expression_system_vector_type: plasmid
mol_id organism_scientific
2
synthetic: yes
other_details: sequence appear naturally in Homo sapiens
Authors : Groft, C.M., Burley, S.K.
Keywords : NSP3; homodimer; eIF4G; Rotavirus; translation; mRNA; closed loop; coiled coil, Viral protein- translation COMPLEX
Exp. method : X-RAY DIFFRACTION ( 2.38 Å )
Citation :

Recognition of eIF4G by rotavirus NSP3 reveals a basis for mRNA circularization.

Groft, C.M.,Burley, S.K.
(2002)  Mol.Cell  9 : 1273 - 1283

PubMed: 12086624
DOI: 10.1016/S1097-2765(02)00555-5

Chain : A, B
UniProt : P03536 (NSP3_ROTS1)
Reaction : -
Chain : C, D
UniProt : Q04637 (IF4G1_HUMAN)
Reaction : -