Brand  (β version)

PDB ID: 1LDE

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
ZN Zinc ion PoSSuM
NAD Nicotinamide-adenine-dinucleotide PoSSuM
FPI N-formylpiperidine PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 1LDE   PDBj   RCSB PDB   PDBe
Header : DEHYDROGENASE
Title : HORSE LIVER ALCOHOL DEHYDROGENASE COMPLEXED TO NADH AND N-FORMYL PIPERDINE
Release Data : 1997-04-01
Compound :
mol_id molecule chains synonym
1 LIVER ALCOHOL DEHYDROGENASE A,B,C,D ADH
ec: 1.1.1.1
Source :
mol_id organism_scientific organism_common
1 Equus caballus  (taxid:9796) Horse
organ: LIVER
cellular_location: CYTOPLASM
other_details: COMMERCIAL PREPARATION OF ENZYME FROM HORSE LIVER. CDNA SEQUENCE M64864
Authors : Ramaswamy, S., Plapp, B.V.
Keywords : DEHYDROGENASE, ALCOHOL, NICOTINAMIDE COENZYME, FORMAMIDES, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.5 Å )
Citation :

Binding of formamides to liver alcohol dehydrogenase.

Ramaswamy, S.,Scholze, M.,Plapp, B.V.
(1997)  Biochemistry  36 : 3522 - 3527

PubMed: 9132002
DOI: 10.1021/bi962491z

Flexibility of Liver Alcohol Dehydrogenase in Stereoselective Binding of 3-Butylthiolane 1-Oxides

Cho, H.,Ramaswamy, S.,Plapp, B.V.
(1997)  Biochemistry  36 : 382

Binding of Substrate in a Ternary Complex of Horse Liver Alcohol Dehydrogenase

Eklund, H.,Plapp, B.V.,Samama, J.P.  et al.
(1982)  J.Biol.Chem.  257 : 14349

Structure of a Triclinic Ternary Complex of Horse Liver Alcohol Dehydrogenase at 2.9 A Resolution

Eklund, H.,Samma, J.P.,Wallen, L.  et al.
(1981)  J.Mol.Biol.  146 : 561

Three-Dimensional Structure of Horse Liver Alcohol Dehydrogenase at 2.4 A Resolution

Eklund, H.,Nordstrom, B.,Zeppezauer, E.  et al.
(1976)  J.Mol.Biol.  102 : 27

Reaction

Chain : A, B, C, D
UniProt : P00327 (ADH1E_HORSE)
Reaction: EC: Evidence:
Physiological Direction:
a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH 1.1.1.1 -
-
a secondary alcohol + NAD(+) = a ketone + H(+) + NADH 1.1.1.1 -
-