Het-PDB Navi2 (PDB: 1L1Q)

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Ligands
Code	Name		Style	Show	Link
9DA	9-deazaadenine				PoSSuM
SO4	Sulfate ion				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1L1Q

Code :

1L1Q PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Crystal Structure of APRTase from Giardia lamblia Complexed with 9-deazaadenine

Release Data :

2002-11-27

Compound :

mol_id	molecule	chains
1	Adenine phosphoribosyltransferase	A
	ec: 2.4.2.7

Source :

mol_id	organism_scientific	expression_system
1	Giardia intestinalis (taxid:5741)	Escherichia coli (taxid:562)

Authors :

Shi, W., Sarver, A.E., Wang, C.C., Tanaka, K.S., Almo, S.C., Schramm, V.L.

Keywords :

adenine, APRTase, Giardia lamblia, purine metabolism, catalytic loop, TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 1.85 Å )

Citation :

Closed Site Complexes of Adenine Phosphoribosyltransferase from Giardia lamblia Reveal a Mechanism of Ribosyl Migration.

Shi, W.,Sarver, A.E.,Wang, C.C. et al.
(2002) J.Biol.Chem. 277 : 39981 - 39988

Chain :

UniProt :

Q967M2 (Q967M2_GIAIN)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine	2.4.2.7	ARBA:ARBA00000868
	-	ARBA:ARBA00000868

PDB ID: 1L1Q