Brand  (β version)

PDB ID: 1KZL

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Ligands
Code Name Style Show Link
CRM 3-[8-((2s,3s,4r)-2,3,4,5-tetrahydroxypentyl)-2,4,7-trioxo-1,3,8-trihydropteridin-6-yl]propanoic acid PoSSuM
HG Mercury (II) ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1KZL   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Riboflavin Synthase from S.pombe bound to Carboxyethyllumazine
Release Data : 2002-11-06
Compound :
mol_id molecule chains synonym
1 Riboflavin Synthase A riboflavin synthase alpha chain
ec: 2.5.1.9
Source :
mol_id organism_scientific organism_common expression_system
1 Schizosaccharomyces pombe  (taxid:4896) Fission yeast Escherichia coli  (taxid:562)
expression_system_vector_type: plasmid
expression_system_plasmid: pNCO113
Authors : Gerhardt, S., Schott, A.K., Kairies, N., Cushman, M., Illarionov, B., Eisenreich, W., Bacher, A., Huber, R., Steinbacher, S., Fischer, M.
Keywords : biosynthesis of riboflavin, riboflavin synthase, Schizosaccharomyces pombe, ligand binding, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.1 Å )
Citation :

Studies on the Reaction Mechanism of Riboflavin Synthase; X-Ray Crystal Structure of a Complex with 6-Carboxyethyl-7-Oxo-8-Ribityllumazine

Gerhardt, S.,Schott, A.K.,Kairies, N.  et al.
(2002)  STRUCTURE  10 : 1371 - 1381

PubMed: 12377123
DOI: 10.1016/S0969-2126(02)00864-X

Reaction

Chain : A
UniProt : Q9Y7P0 (RISA_SCHPO)
Reaction: EC: Evidence:
Physiological Direction:
2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) = 5-amino-6-(D- ribitylamino)uracil + riboflavin 2.5.1.9 PubMed:14690539
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