Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
CA3 Coa-S-trimethylene-acetyl-tryptamine
Code : 1KUX
Header : TRANSFERASE
Title : X-ray Crystallographic Studies of Serotonin N-acetyltransferase Catalysis and Inhibition
Release Data : 2002-03-22
Compound :
mol_id molecule chains synonym
1 Serotonin N-acetyltransferase A arylalkylamine N-acetyltransferase; Aralkylamine N-acetyltransferase; AA-NAT; Serotonin acetylase
ec: 2.3.1.87
mutation: MET substituted by Se-met
Source :
mol_id organism_scientific organism_common expression_system
1 Ovis aries  (taxid:9940) Sheep Escherichia coli  (taxid:562)
gene: U29663
expression_system_strain: BL21(DE3)pLysS
expression_system_vector_type: Plasmid
expression_system_plasmid: pGEX-6P-1
Authors : Wolf, E., De Angelis, J., Khalil, E.M., Cole, P.A., Burley, S.K.
Keywords : Enzyme-Inhibitor Complex, Bisubstrate Analog, Alternate Conformations, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.80 Å )
Citation :

X-ray crystallographic studies of serotonin N-acetyltransferase catalysis and inhibition.

Wolf, E.,De Angelis, J.,Khalil, E.M.  et al.
(2002)  J.Mol.Biol.  317 : 215 - 224

PubMed: 11902838
DOI: 10.1006/jmbi.2001.5371

Chain : A
UniProt : Q29495 (SNAT_SHEEP)
Reaction : Acetyl-CoA + a 2-arylethylamine = CoA + an N- acetyl-2-arylethylamine.