Brand  (β version)

PDB ID: 1KSB

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Ligands
Code Name Style Show Link
CPT Cisplatin PoSSuM
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Glycosylation
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Structure summary

Code : 1KSB   PDBj   RCSB PDB   PDBe
Header : DNA
Title : Relationship of Solution and Protein-Bound Structures of DNA Duplexes with the Major Intrastrand Cross-Link Lesions Formed on Cisplatin Binding to DNA
Release Data : 2002-01-17
Compound :
mol_id molecule chains
1 5'-D(*CP*TP*CP*CP*GP*GP*CP*CP*T)-3' A
other_details: Cisplatin intrastrand cross-link DNA
mol_id molecule chains
2 5'-D(*AP*GP*GP*CP*CP*GP*GP*AP*G)-3' B
Source :
mol_id organism_scientific
1
synthetic: yes
mol_id organism_scientific
2
synthetic: yes
Authors : Marzilli, L.G., Saad, J.S., Kuklenyik, Z., Keating, K.A., Xu, Y.
Keywords : Deoxyribonucleic acid, Cisplatin, DNA, Duplex, 9-mer, Intrastrand cross-link, model J
Exp. method : SOLUTION NMR
Citation :

Relationship of solution and protein-bound structures of DNA duplexes with the major intrastrand cross-link lesions formed on cisplatin binding to DNA.

Marzilli, L.G.,Saad, J.S.,Kuklenyik, Z.  et al.
(2001)  J.Am.Chem.Soc.  123 : 2764 - 2770

PubMed: 11456962
DOI: 10.1021/ja0007915