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Ligands
Code Name Style Show Link
FE2 Fe (II) ion
MBD 3-methylcatechol
TBU Tertiary-butyl alcohol
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Code : 1KNF   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal Structure of 2,3-dihydroxybiphenyl 1,2-dioxygenase Complexed with 3-methyl Catechol under Anaerobic Condition
Release Data : 2002-03-27
Compound :
mol_id molecule chains synonym
1 2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE A Biphenyl-2,3-diol 1,2-dioxygenase, DHBD
ec: 1.13.11.39
Source :
mol_id organism_scientific expression_system
1 Burkholderia xenovorans  (taxid:266265) Burkholderia cepacia  (taxid:292)
strain: LB400
gene: BPHC
expression_system_vector_type: PLASMID
expression_system_plasmid: PLEBD4
other_details: HYPEREXPRESSED IN THE PARENT STRAIN (This organism has been reclassified. Prior publications may refer to this source as Pseudomonas sp. strain LB400.)
Authors : Han, S., Bolin, J.T.
Keywords : dioxygenase, 2, 3-dihydroxybiphenyl, 3-methyl catechol, oxidoreductase
Exp. method : X-RAY DIFFRACTION ( 1.9 Å )
Citation :

Molecular basis for the stabilization and inhibition of 2, 3-dihydroxybiphenyl 1,2-dioxygenase by t-butanol.

Vaillancourt, F.H.,Han, S.,Fortin, P.D.  et al.
(1998)  J.Biol.Chem.  273 : 34887 - 34895

PubMed: 9857017
DOI: 10.1074/jbc.273.52.34887

Crystal Structure of the Biphenyl-cleaving Extradiol Dioxygenase from a PCB-degrading Pseudomonad.

Han, S.,Eltis, L.D.,Timmis, K.N.  et al.
(1995)  Science  270 : 976 - 980

2,3-Dihydroxybiphenyl 1,2-dioxygenase.

Bolin, J.T.,Eltis, L.D.
(2001)  Handbook of Metalloproteins  : 632 - 642

Chain : A
UniProt : P47228 (BPHC_PARXL)
Reaction: EC: Evidence:
Physiological Direction:
biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4- dienoate + H(+) 1.13.11.39 -
-